BioNukleo - combining biocatalysis and nucleosides
Enzymatic synthesis of nucleosides, nucleotides, and their derivatives
At BioNukleo, we harness the power of enzymes to provide sustainable solutions for the synthesis of various fine chemicals, focusing on nucleoside and nucleotide derivatives and related compounds. By combining our extensive knowledge about biocatalysis and nucleosides we can provide custom biocatalytic solutions with high selectivity and reduced environmental impact, aligning with the demand for sustainable chemical manufacturing.
Discover Our Services
Process Development
Achieve more sustainable and cost-effective nucleoside or nucleotide synthesis by implementing nature's own catalysts. Together we will find a solution to create your desired fine-chemical or improve and facilitate your existing process.
Protein Production
Are you in need of a special protein or a specific enzyme property that is not yet part of our catalogue? We will assist you to find the right enzyme candidate and produce it for you. Production is optimized in high-throughput and can be scaled-up in-house up to 100-liter.
Custom Products
Leveraging decades of experience, we offer rapid and cost-effective enzymatic synthesis of nucleoside 5'-triphosphates at µmol scale. Simply provide your nucleoside substrate, and we'll tailor our process to your needs and create your desired NTP for you.
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Enzymes
Browse through our extensive portfolio of nucleoside, nucleotide, or sugar modifying biocatalysts - from A like Acetate kinase to X like Xanthosine phosphorylase.
Kits
Measure inorganic (pyro-) phosphate levels by utilizing biocatalysis in the PUB assay; or make use of our carefully assembled sets of enzymes for various purposes.
Fine Chemicals
Choose from selected sugar-1-phosphates, organic phosphate donors such as acetyl phosphate, or nucleoside 5'-triphosphates such as 5-formyl-dCTP.
