Enzymatic synthesis of modified nucleosides and nucleotides


BioNukleo set up enzyme libraries for nucleoside phoshorylases and nucleoside/nucleotide kinases. The enzymes are well characterized and possess a large substrate promiscuity. Detailed protocols were developed which enable customers to produce nucleoside and nucleotide analogues which high yields and excellent purity.



BioNukleo offers the development of custom-specific synthesis routes for the enzymatic production of modified nucleosides and nucleotides. Furthermore, BioNukleo offers customized contract research.


BioNukleo offers a wide variety of enzymes and detailed protocols for the custom-specific synthesis of natural and modified nucleosides and nucleotides. To enhance nucleoside synthesis sugar-1-phosphates are also available.


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