BioNukleo - Your partner for the synthesis of modified nucleosides and nucleotides!

BioNukleo was founded in 2014 as a spin-off of the Department of Bioprocess Engineering of Technische Universität Berlin.


Based on long-standing experience in the enzymatic synthesis of nucleoside analogs and the production of difficult to express proteins, BioNukleo developed to a specialist for the (chemo-) enzymatic production of nucleic acid derivatives. BioNukleo's technology is based on the use of biocatalysts for the efficient synthesis of nucleoside and nucleotide analogs in one-pot and sustainable reactions.